Isolators are cleanroom modules that function under a defined differential pressure in order to fully separate a process area from the operator. In the life-science industry in particular, isolators have become indispensable. They make it possible to control the environment and reduce the contamination risk during aseptic processing. The isolator systems of the Ortner Group were developed by drawing on many years of experience with this technology. The models are being further developed through extensive research work and are being optimized through practical use requirements. Ortner isolators fit the paradigm of integrated innovation, can be used in many different ways, and offer numerous advantages compared to many other cleanroom solutions: from minimization of risk to energy efficiency.